While there are several causes or associations for CP, including genetic mutations,8 preterm delivery is a major risk factor and accounts for approximately 35% of all cases.

Offer intravenous magnesium sulfate for neuroprotection of the baby to women between 24+0 and 29+6 weeks of pregnancy who are:
•in established preterm labour or
•having a planned preterm birth within 24 hours

Meta-analyses report encouraging results that are consistent with a
modest but tangible benefit for the use of MgSO4, and suggest a
number needed to treat (NNT) to prevent one in 46 cases of CP in
infants born preterm before 30 weeks of gestation and one in 63
cases of CP in infants born preterm before 34 weeks of gestation.