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z5 Obstetric Cholestasis

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1. Q9 OC

What is the optimal gestational age for delivery in Obstetric Cholestasis with severe biochemical abnormality?

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2. Q6 OC
A Primigravida at 34 weeks gestation, with Obstetric Cholestasis is on regular follow up.
Today her labs are as follows- AST- 62 IU/L, ALT 63 IU/l, Bile acids - 27 micromol /L. Prothrombin time is 15 sec( Normal 9.6 to 12.9 sec) . She is on appropriate dose of Ursodeoxycholic acid. What other treatment should be advised?

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